Established in 2020 Wednesday, June 12, 2024

3D printing technology for tissue: Researchers combine hydrogels and fibers
Graphic of the 3D bio-printing method. Image courtesy: Universität Bayreuth.

BAYREUTH.- In the latest study by Prof. Dr. Leonid Ionov, Professor of Biofabrication, and his team at the University of Bayreuth, various types of hydrogels were extensively tested for the 3D printing of tissues. A hydrogel is a water-retaining and also water-insoluble polymer. In addition, the cell containing–hydrogels, also known as bioink, are combined with fibers to create a composite material.

This is achieved by using 3D (bio) printing with an integrated touch-spinning process. Touch spinning is a scalable process for producing fibers from a polymer solution or melt. The Bayreuth scientists have now combined 3D (bio) printing technology with touch-spinning technology in a single device for the first time.

"The insights gained in this study are of great importance for the production of tissues and in particular tissues with fibrous structures and uniaxial alignment of cells such as connective and muscle tissue," explains Prof. Dr. Ionov.

In their article recently published in the journal Advanced Healthcare Materials, Prof. Dr. Ionov, along with Bayreuth researchers Prof. Dr. Dr. Elisabetta Ada Cavalcanti-Adam, Chair of Cellular Biomechanics, Waseem Kitana, Ph.D. student at the Chair of Biofabrication, and their colleague Dr. Victoria Levario-Diaz from the Max Planck Institute for Medical Research, report on a novel approach for the production of multilayer bioink fiber composites.

The Bayreuth scientists used various hydrogels in the experiments and compared their properties. Hydrogels have been widely used as scaffold materials in the fields of tissue engineering and biofabrication for decades. Tissue engineering is the umbrella term for the artificial production of biological tissues.

The combination of a hydrogel system with a fiber system reduces the processing requirements for hydrogels, such as cross-linking to improve their mechanical properties, as the mechanical properties of these composite materials are covered by the fiber system. In addition, the requirement for a low degree of cross-linking is advantageous for subsequent tissue formation.

"The hydrogel provides the cells with an aqueous environment that promotes the good functioning of the cells, while the fibers should control the orientation of the cells along the main direction of the fiber," says Prof. Dr. Ionov.

Today's News

February 10, 2024

New fossil site of worldwide importance uncovered in southern France

Scandinavia's first farmers slaughtered the hunter-gatherer population

MIT physicists capture the first sounds of heat "sloshing" in a superfluid

First complete genome sequencing of a snakefly helps to understand its evolutionary history

Nanofiber bandages fight infection, speed healing

Researchers measure and control interactions between magnetic ripples using lasers

Ice cores provide first documentation of rapid Antarctic ice loss in the past

On Hawaii's Kilauea, little stresses add up

Probing proton pumping: New findings on protein folding in bacteriorhodopsin

Researchers discover one million new components of the human genome

Global study: Wild megafauna shape ecosystem properties

Faulty DNA disposal system causes inflammation

3D brain mapping opens a window to the aging brain

Research team takes a fundamental step toward a functioning quantum internet

3D printing technology for tissue: Researchers combine hydrogels and fibers

Harnessing light-powered nanoscale electrical currents to propel emerging technologies

Sitting idle boosts the performance of lithium metal batteries for next-generation EVs

Why olivine and diamonds are best friends

Technique could improve the sensitivity of quantum sensing devices

How one type of lung cancer can transform into another

Scientists develop a low-cost device to make cell therapy safer

New research with implications for drug discovery makes it possible to visualize the smallest protein clusters

Fusion research facility's final tritium experiments yield new energy record

Scientists uncover a new model for the effects of radiation in water systems


Editor & Publisher: Jose Villarreal
Art Director: Juan José Sepúlveda Ramírez

Tell a Friend
Dear User, please complete the form below in order to recommend the ResearchNews newsletter to someone you know.
Please complete all fields marked *.
Sending Mail
Sending Successful